MovDisordV3, France, Analysis, bibRecord, 000389

Cerebral autoregulation is preserved in multiple system atrophy : A transcranial doppler study

Identifieur interne : 000389 ( France/Analysis ); précédent : 000388; suivant : 000390

Cerebral autoregulation is preserved in multiple system atrophy : A transcranial doppler study

Auteurs : Anne Pavy-Le Traon [France] ; Richard L. Hughson [Canada] ; Claire Thalamas [France] ; Monique Galitsky [France] ; Nelly Fabre [France] ; Olivier Rascol [France] ; Jean-Michel Senard [France]

Source :

Movement disorders [ 0885-3185 ] ; 2006.

RBID : Pascal:07-0090864

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Atrophie multisystématisée, Système nerveux autonome pathologie, Hypotension artérielle orthostatique, Encéphale, Autorégulation, Dopplérométrie, Analyse spectrale.

English descriptors

KwdEn :
- Diseases of the autonomic nervous system, Doppler ultrasound study, Encephalon, Multiple system atrophy, Nervous system diseases, Postural hypotension, Self regulation, Spectral analysis.

Abstract

Patients with multiple system atrophy (MSA) present large changes in blood pressure (BP) due to autonomic disturbances. We analyzed how this change may influence dynamic cerebral autoregulation (DCA). Simultaneous recordings of arterial BP (Finapres) and middle cerebral artery (MCA) blood flow velocity (BFV) (transcranial Doppler) were performed in 10 patients with MSA (61 ± 12 yr of age) and 12 healthy volunteers (61 ± 11 yr of age): cerebral BFV response to oscillations in mean BP was studied in the supine position by cross-spectral analysis of mean BP and mean MCA BFV. The DCA was also studied during the decrease in BP the first seconds when standing up from a sitting position by the assessment of the cerebrovascular resistance index (CR; mean BP/mean MCA BFV ratio). The MCA BFV/BP cross-spectral analysis showed a phase for the mid-frequency band (0.07-0.2 Hz) significantly larger in MSA, suggesting more active autoregulation in response to larger changes in BP. Changes in CR reflecting the rate of autoregulation, when standing did not differ between the two groups. These data suggest that dynamic cerebral autoregulation is preserved in MSA.

Affiliations:

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Pascal:07-0090864

Le document en format XML

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<term>Nervous system diseases</term>
<term>Postural hypotension</term>
<term>Self regulation</term>
<term>Spectral analysis</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
<term>Atrophie multisystématisée</term>
<term>Système nerveux autonome pathologie</term>
<term>Hypotension artérielle orthostatique</term>
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<front><div type="abstract" xml:lang="en">Patients with multiple system atrophy (MSA) present large changes in blood pressure (BP) due to autonomic disturbances. We analyzed how this change may influence dynamic cerebral autoregulation (DCA). Simultaneous recordings of arterial BP (Finapres) and middle cerebral artery (MCA) blood flow velocity (BFV) (transcranial Doppler) were performed in 10 patients with MSA (61 ± 12 yr of age) and 12 healthy volunteers (61 ± 11 yr of age): cerebral BFV response to oscillations in mean BP was studied in the supine position by cross-spectral analysis of mean BP and mean MCA BFV. The DCA was also studied during the decrease in BP the first seconds when standing up from a sitting position by the assessment of the cerebrovascular resistance index (CR; mean BP/mean MCA BFV ratio). The MCA BFV/BP cross-spectral analysis showed a phase for the mid-frequency band (0.07-0.2 Hz) significantly larger in MSA, suggesting more active autoregulation in response to larger changes in BP. Changes in CR reflecting the rate of autoregulation, when standing did not differ between the two groups. These data suggest that dynamic cerebral autoregulation is preserved in MSA.</div>
</front>
</TEI>
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<tree><country name="France"><noRegion><name sortKey="Pavy Le Traon, Anne" sort="Pavy Le Traon, Anne" uniqKey="Pavy Le Traon A" first="Anne" last="Pavy-Le Traon">Anne Pavy-Le Traon</name>
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<name sortKey="Fabre, Nelly" sort="Fabre, Nelly" uniqKey="Fabre N" first="Nelly" last="Fabre">Nelly Fabre</name>
<name sortKey="Galitsky, Monique" sort="Galitsky, Monique" uniqKey="Galitsky M" first="Monique" last="Galitsky">Monique Galitsky</name>
<name sortKey="Pavy Le Traon, Anne" sort="Pavy Le Traon, Anne" uniqKey="Pavy Le Traon A" first="Anne" last="Pavy-Le Traon">Anne Pavy-Le Traon</name>
<name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name>
<name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name>
<name sortKey="Senard, Jean Michel" sort="Senard, Jean Michel" uniqKey="Senard J" first="Jean-Michel" last="Senard">Jean-Michel Senard</name>
<name sortKey="Senard, Jean Michel" sort="Senard, Jean Michel" uniqKey="Senard J" first="Jean-Michel" last="Senard">Jean-Michel Senard</name>
<name sortKey="Thalamas, Claire" sort="Thalamas, Claire" uniqKey="Thalamas C" first="Claire" last="Thalamas">Claire Thalamas</name>
</country>
<country name="Canada"><noRegion><name sortKey="Hughson, Richard L" sort="Hughson, Richard L" uniqKey="Hughson R" first="Richard L." last="Hughson">Richard L. Hughson</name>
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   |texte=   Cerebral autoregulation is preserved in multiple system atrophy : A transcranial doppler study
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	Movement Disorders (revue)
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Movement Disorders (revue)

Cerebral autoregulation is preserved in multiple system atrophy : A transcranial doppler study

Cerebral autoregulation is preserved in multiple system atrophy : A transcranial doppler study

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri